I'm not a HUGE hot sauce fan, but just about everyone else in my life is!  For most, it's "the hotter, the better".  I guess I have what you'd call a "sensitive palate".  At one point, Big Red gum was too spicy for me.

Hot sauce specialty shop
John Greim

As far as hot sauces go, though, Frank's is my favorite.  I'm sure some of it is because I'm born and raised in WNY and it's practically our holy water....but also, I like that there's more flavor than heat to it.

Thrillist.com just ranked the top 10 hot sauces...here were their results:

What say you, Buffalo? (Feel free to add your own!)