The Buffalo Bills kick off their season tonight on the road against the defending Super Bowl champions the Los Angeles Rams.

The Bills are the odds-on favorites to win the Super Bowl but each and every NFL season has its up and downs. Not since 1972 has a team won every single game they played in a season. So here is my week-by-week predictions for how the Bills' season will shake out.

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Spoiler - I have them winning the Super Bowl this year.

 

Week One - Away - Los Angeles Rams - Win 35-21 - The Bills open up the season on the road in LA to open the season on Thursday night. The Bills' first statement to the league is a big win.

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Week Two - Home - Tennessee Titans - Win 28-10 - The Bills start the season with two Primetime wins taking out the Titans on Monday Night.

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Week Three - Away - Miami Dolphins - Win 42-17 - The Bills get their first AFC East win over rival Miami. Buffalo squishes the fish on the road.

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Week Four - Away - Baltimore Ravens - Loss 21-14 - The Bills suffer their first loss of the season on the road in a tough bad weather game against the Ravens.

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Week Five - Home - Pittsburgh Steelers - Win 35-19 - The Bills get revenge for last season's home opener loss to the Steelers.

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Week Six - Away - Kansas City Chiefs - Loss 42-35 - The Bills drop another high-scoring game to the Chiefs on the road.

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Week Seven - BYE Week - The Bills head into the Bye week with a 4-2 record.

Week Eight - Home - Green Bay Packers - Win 35-13 - With an extra week to prepare, the Bills return to their winning ways on Primetime with a big win over Green Bay.

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Week Nine - Away - New York Jets - Loss 28-10 - The Bills fall to 2nd in the AFC East with a loss to rival Jets on the road.

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Week Ten - Home - Minnesota Vikings - Win 35-7 - Stefon Diggs helps prove the Bills won the trade by going off for three TDs.

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Week Eleven - Home - Cleveland Browns - Win 33-17 - The Bills prove that there is only one "mistake by the lake" and it is Cleveland.

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Week Twelve - Away - Detroit Lions - Win 42-10 - Josh Allen and Crew grab another win and another giant turkey leg with a win on Thanksgiving.

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Week Thirteen - Away - New England Patriots - Win 28-10 - Another Primetime win and another almost perfect game for Josh Allen as the Bills beat the Pats on Thursday Night Football.

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Week Fourteen - Home - New York Jets - Win 42-10 - The Bills get revenge for an earlier season loss and beat the Jets at home.

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Week Fifteen - Home - Miami Dolphins - Win 28-10 - The Bills clinch the AFC East with a win over the Dolphins.

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Week Sixteen - Away - Chicago Bears - Loss 21-10 - The Bills' winning streak is snapped on the road in Chicago.

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Week Seventeen - Away - Cincinnati Bengals - Win 35-28 - The Bills clinch the #1 seed in the AFC with a win over last season's champs.

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Week Eighteen - Home - New England Patriots - Loss 21-3 - The Bills opt to rest their starters and the backups fall to Mac and Company to end the regular season.

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The Bills will clinch the #1 seed in the AFC with a 12-5 record and home-field advantage in the playoffs.

They will win both home playoff games before winning the Super Bowl to bring the Lombardi Trophy to Western New York for the first time in franchise history.

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