It's finally here. The 2022 NFL regular season matchup that every NFL fan has been looking forward to.

The Buffalo Bills will play at the Kansas City Chiefs at Arrowhead Stadium this Sunday at 4:25 p.m.

The week 6 game is the one game that CBS decided to hold on to when the NFL was deciding on their schedule, because surely it would have been a Sunday Night Football game had it not been the national game in the 4:25 pm slot this week.

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It's the rematch of the AFC Divisional round game back in January, which many claim is the best NFL playoff game of all-time and maybe even the best NFL game ever, period.

The Bills lost 42-36 in overtime and yes, everyone has heard it one million times by now -- "13 seconds."

The Bills and Chiefs are both 4-1 and at the top of the AFC standings after five weeks, but what may surprise some fans is that Buffalo is actually favored on the road.

The Bills are not just favored against the 4-1 Chiefs, they're 3-point favorites on the road at Arrowhead Stadium.

The Bills are favored by three points because of how they have won their games this season.

The Bills blew out the Los Angeles Rams, Tennessee Titans and Pittsburgh Steelers. They weren't just blow outs, they were complete and utter domination of those teams and while the Bills dealt with injuries.

The other win came in a 17-point comeback on the road against Lamar Jackson and the Baltimore Ravens in heavy rain. Their only loss came against the Miami Dolphins in intense heat and humidity, minus many starters, and the Bills still outgained the Dolphins by 280 yards...

The Chiefs had a nice comeback win themselves last night against the Las Vegas Raiders, down 17 points. However, they lost to the Indianapolis Colts (who look horrible this season) and their only two blowout wins came against the Arizona Cardinals (who look like a bad team) and the Tampa Bay Buccaneers, which was a rematch of their Super Bowl defeat.

Overall, the Bills have been the better team this season and on paper are better than the Chiefs.

Kansas City still has Patrick Mahomes at quarterback and Andy Reid scheming plays, so as long as that factor exists, the Chiefs will always be a contender and will be capable of beating Buffalo on Sunday.

The Bills will have to take advantage of the Chiefs secondary, which looks like a mismatch against Allen and the Bills passing offense.

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